Cell biology

  • All
  • Action
  • Document
  • Guide
  • Manip
  • News
  • Outreach
  • Ressources
maria-elena-torres padilla
Maria-Elena Torres-Padilla

Research in Maria-Elena Torres-Padilla’s laboratory focuses on understanding how early mouse development is regulated by chromatin-mediated changes in gene regulation, that is, by epigenetic information. In particular, we are interested in understanding how the transitions in cell potency and cell fate are regulated by chromatin-mediated processes. ...

Journot
Laurent Journot

We each have two versions or alleles of each gene, one from our father, one from our mother. Parental genomic imprinting is an epigenetic mechanism that restrains the expression of an allele depending on its origin, paternal or maternal. 

The alteration of this process at defined loci results in different...

levashina
Elena Levashina

Elena Levashina is focusing on building on the research she developed on the role of the immune system in regulating the survival of malaria parasites in the Anopheles mosquito, the insect vector that transmits malaria to humans. She and her group now have a greater focus on the vector biology,...

soutoglou
Evi Soutoglou

Evi Soutoglou is interested in the most deleterious DNA breaks amongst the thousands of lesions our that DNA suffers in each of our cells every day : the Double Strand Breaks (DSB). Her goal is to investigate the dynamics of DSBs in relation to the surrounding chromatin structure and nuclear...

geissmann-2
Frédéric Geissmann

The Mononuclear Phagocyte System (MPS) is a group of cells with crucial functions in our immune system: it mediates and regulates inflammation. However, it is not only a powerful mechanism to control proliferation of microorganisms, it also –unfortunately- damages host tissues and contributes in the long term to many features...

girault-3
Jean-Antoine Girault

Jean-Antoine Girault aims to identify the intracellular signalization mechanisms which underlie long term behavioral changes. The ability of the nervous system to adapt to a variable environment indeed depends on the modulation and plasticity of synapses between these neurons, which is regulated by their activity and by multiple neuromodulators....

heard
Edith Heard

X-inactivation is a process by which one of the two X chromosomes is transcriptionally silenced during early development in female mammals. It allows for dosage compensation between XX females and XY males. Edith Heard is studying this paradigm for developmental epigenetics to gain insights into the fundamental mechanisms that underlie...

jean-rene-huynh
Jean-René Huynh

Understanding how germ cells develop is not only of paramount medical interest for reproductive medicine, but is also crucial to comprehend how animal shapes and forms evolve through generations. Jean-René Huynh and his team are focusing on how the genetic information (through meiosis) and epigenetic information (through small RNAs)...

bettencourt dias
Monica Bettencourt-Dias

Mónica Bettencourt-Dias studies crucial structures in our cells, centrioles and cilia. She is investigating their biogenesis, evolution and misregulation using a variety of approaches, model organisms and patient samples....

sandrine-etienne-manneville
Sandrine Etienne-Manneville

Sandrine Etienne-Manneville focuses her research on cell migration and cell polarity. Cellular migration plays a key role in both developing organisms and adults ones, where it is involved in the immune response, scar tissue formation, or the dissemination of tumor cells. Cell polarity is fundamental for migration both for its...