Epigenetics

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Jérome dejardin
Jérôme Déjardin

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picture of Reini Luco
Reini F. Luco

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Pablo Navarro
Pablo Navarro

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soler pic
Eric Soler

Research in Maria-Elena Torres-Padilla’s laboratory focuses on understanding how early mouse development is regulated by chromatin-mediated changes in gene regulation, that is, by epigenetic information. In particular, we are interested in understanding how the transitions in cell potency and cell fate are regulated by chromatin-mediated processes. ...

manolis
Manolis Papamichos-Chronakis

The overall objective of Manolis Papamichos-Chronakis group is to decipher the interplay between the multiple machineries that keep our genome intact and the chromatin structure of DNA. Using a combination of genetics, cell imaging and high-throughput technologies in budding yeast and human cells they are exploring the role of chromatin...

maria-elena-torres padilla
Maria-Elena Torres-Padilla

Research in Maria-Elena Torres-Padilla’s laboratory focuses on understanding how early mouse development is regulated by chromatin-mediated changes in gene regulation, that is, by epigenetic information. In particular, we are interested in understanding how the transitions in cell potency and cell fate are regulated by chromatin-mediated processes. ...

Journot
Laurent Journot

We each have two versions or alleles of each gene, one from our father, one from our mother. Parental genomic imprinting is an epigenetic mechanism that restrains the expression of an allele depending on its origin, paternal or maternal. 

The alteration of this process at defined loci results in different...

heard
Edith Heard

X-inactivation is a process by which one of the two X chromosomes is transcriptionally silenced during early development in female mammals. It allows for dosage compensation between XX females and XY males. Edith Heard is studying this paradigm for developmental epigenetics to gain insights into the fundamental mechanisms that underlie...

cavalli portrait
Giacomo Cavalli

Giacomo Cavalli is investigating heredity and gene regulation laws beyond DNA sequence. He and his lab discovered that the 3D structure of chromosomes can be heritable and that it contributes to genome regulation. Furthermore, they provided the first high-resolution description of the principles of genome folding in animals. Finally, the...

arnaud-echard
Arnaud Echard

Arnaud Echard is interested in the role of membrane trafficking in lipid and cytoskeleton remodeling at each step of animal cell division....