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dejardin
Jérôme Déjardin

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picture of Reini Luco
Reini F. Luco

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Pablo Navarro
Pablo Navarro

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navarro
Lionel Navarro

Lionel Navarro’s current research interests are to understand the role and regulation of small RNAs in plant and human innate immunity and to unravel the mechanisms by which bacterial effectors interfere with RNA silencing. His research also aims at deciphering the role of RNA silencing in the evolution of the...

eichmann-21
Anne Eichmann

Vertebrate blood vessels form stereotyped, hierarchical branched networks. Specialized endothelial cells (EC) called tip cells located at the extremities of growing capillary sprouts mediate their directional outgrowth. Research in Anne Eichmann’s laboratory is aimed at understanding the function of tip cell-specific signaling molecules, with the goal to manipulate guided vascular...

heard
Edith Heard

X-inactivation is a process by which one of the two X chromosomes is transcriptionally silenced during early development in female mammals. It allows for dosage compensation between XX females and XY males. Edith Heard is studying this paradigm for developmental epigenetics to gain insights into the fundamental mechanisms that underlie...

reina-san-martin-3
Bernardo Reina San Martin

Bernardo Reina San Martin is interested in the molecular mechanisms driving the diversification of the repertoire of B-cells, the cells of our immune system producing antibodies. He specifically investigates somatic hypermutation (SHM) and class switch recombination (CSR), two processes involved in the immune response to generate an antibody mediated answer,...

patrick-mehlen
Patrick Mehlen

In adults, cell renewal is precisely controlled, notably by a mechanism involving Dependence Receptors in the control of cell death. In certain cancers, cells escape this process, which gives them a supplementary selective advantage to uncontrollably multiply and form tumors. Patrick Mehlen deciphers those mechanisms to offer novel ways to...

delmas
Patrick Delmas

Patrick Delmas is interested in sensory neurons that translate thermal, chemical, and mechanical stimuli. His goal is to understand the molecular basis of somatosensation - the process whereby we experience touch and pain - with an emphasis on identifying molecules that regulate electrogenesis of sensory neurons and detect environmental stimuli....

allain-3
Frédéric Allain

Alternative splicing is a process allowing cells to make different products from one gene. Since it was discovered over three decades ago now, it has been shown that it has key roles especially in tissue differentiation and pathologies like hereditary diseases and cancer. Frédéric Allain is determining with his team the...