Molecular biology

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Frédéric Allain

Alternative splicing is a process allowing cells to make different products from one gene. Since it was discovered over three decades ago now, it has been shown that it has key roles especially in tissue differentiation and pathologies like hereditary diseases and cancer. Frédéric Allain is determining with his team the...

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Giacomo Cavalli

Giacomo Cavalli is investigating heredity and gene regulation laws beyond DNA sequence. He and his lab discovered that the 3D structure of chromosomes can be heritable and that it contributes to genome regulation. Furthermore, they provided the first high-resolution description of the principles of genome folding in animals. Finally, the...

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Arnaud Echard

Arnaud Echard is interested in the role of membrane trafficking in lipid and cytoskeleton remodeling at each step of animal cell division....

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Rafal Ciosk

Rafal Ciosk's research focuses on understanding the mechanisms involved in cell fate commitment and reprogramming, universal biological processes. He is using a combination of molecular, biochemical and genomic approaches in the experimental model C. elegans to decipher the molecular regulation of pluripotency in germ cells, which involves mechanisms of mRNA...