2022. Rebekka Wild and her research group are investigating the enzymes involved in glycosaminoglycan biosynthesis on an atomic level. Glycosaminoglycans are long and complex sugar chains found on the cell surface of all animal cells, ranging from sea anemone to humans, and they play an important role in diverse biological...
2020. Frederic Landmann and his team are exploring the symbiotic relationship between Wolbachia bacteria and their parasitic hosts, the filarial nematodes. These worms cause debilitating diseases, the filariasis, and infect 100 million people. They rely on intracellular Wolbachia endosymbionts to produce a progeny and to survive....
2020. Marie Manceau and her research team study the developmental mechanisms that control the formation and the evolution of the exquisitely diverse patterns that adorn the coat of animals. To identify pattern-forming dynamics, they survey and model natural variation in the plumage pattern....
2020. The main focus of our research is understanding how adult stem cells are maintained throughout life, how they generate and regenerate tissues and how they relate to tumor development. We focus on studying how the Notch signalling pathway controls cell fate specification and lineage segregation, in coordination with tissue...
2020. Our group is dedicated to deciphering the mechanisms underlying the pathophysiology of overgrowth syndromes and vascular abnormalities of genetic origin in order to propose new therapies to patients. We have been working for a long time on the PIK3/AKT/mTOR pathway in the context of renal diseases and have progressively...
2019. Francesca Giordano and her team work to figure out the role of membrane contact sites or nearby membrane attachment sites (at 10-30nm) in the transport of lipids between endoplasmic reticulum and other intracellular organelles. The exchange of non-vesicular lipids at membrane contact sites emerges as one of the key...
2019. Sonia Garel and her team work to figure out the mechanisms that regulate the assembly of neural circuits during embryogenesis and after birth, with a particular focus on interactions with the brain's immune cells called microglia. They examine how development programs and microglia coordinate the assembly of millions of...
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