2020. Our group is dedicated to deciphering the mechanisms underlying the pathophysiology of overgrowth syndromes and vascular abnormalities of genetic origin in order to propose new therapies to patients. We have been working for a long time on the PIK3/AKT/mTOR pathway in the context of renal diseases and have progressively...
2019. Francesca Giordano and her team work to figure out the role of membrane contact sites or nearby membrane attachment sites (at 10-30nm) in the transport of lipids between endoplasmic reticulum and other intracellular organelles. The exchange of non-vesicular lipids at membrane contact sites emerges as one of the key...
2019. Sonia Garel and her team work to figure out the mechanisms that regulate the assembly of neural circuits during embryogenesis and after birth, with a particular focus on interactions with the brain's immune cells called microglia. They examine how development programs and microglia coordinate the assembly of millions of...
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Jérôme Déjardin's lab is focused on understanding the contributions of heterochromatin factors and DNA repeats to genome stability, gene expression and genome evolution....
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