Mónica Bettencourt-Dias studies crucial structures in our cells, centrioles and cilia. She is investigating their biogenesis, evolution and misregulation using a variety of approaches, model organisms and patient samples....
Ivan Rodriguez is exploring the neuronal circuits which are controlling innate behaviors in mammals....
Thomas Lecuit and his team study how epithelial tissues maintain a robust organization and extensively remodel as they grow and change their shape during development....
Alain Chédotal is interested in deciphering how one hand migrating neurons and on the other hand neuron extensions to establish connections between one another (axons) are guided in the developing brain. He is also working with his team on new technologies allowing the visualization of developing neurons. Their research should...
Yohanns Bellaïche aims at understanding how cell fate diversity is generated during development and how organs acquire their shape. Using the Drosophila fruit fly model, his interdisciplinary group develops and uses complementary approaches including multi-scale confocal microscopy, physical measurements and opto-genetics to probe both the physical and genetics regulations that...
Arnaud Echard is interested in the role of membrane trafficking in lipid and cytoskeleton remodeling at each step of animal cell division....
Bénédicte Delaval is interested in understanding the cellular mechanisms controlling cell division and how the disruption of these cellular processes influences the initiation and progression of pathologies such as cystic kidney disease and cancer. More precisely, she and her group are combining cell biology and biochemical approaches in cultured cells...
Patrick Collombat and his research group are studying type I diabetes, an auto-immune disease characterized by the loss of insulin producing cells in the pancreas (the beta cells). Using mice as a model system, they recently demonstrated that ectopic expression of a single gene (Pax4) in neighboring cells of the...
Rafal Ciosk's research focuses on understanding the mechanisms involved in cell fate commitment and reprogramming, universal biological processes. He is using a combination of molecular, biochemical and genomic approaches in the experimental model C. elegans to decipher the molecular regulation of pluripotency in germ cells, which involves mechanisms of mRNA...
Neural stem cells (NSCs) are at the origin of the neurons and glia generated in the adult vertebrate brain. The success of NSC maintenance and mobilization varies widely among species, brain territories, pathological conditions and individual environment, with important physiological impacts. Laure Bally and her team are using the zebrafish model...