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Vallot_photo
Céline Vallot

2021. Céline Vallot and her research group are investigating epigenetic mechanisms driving tumor plasticity. These study how chemical modifications of the chromatin, structuring DNA, play a role in defining the phenotype of cancer cells. They explore the dynamics of acquisition of epigenetic features in cancer cells, to understand how these...

Silvia Fre - Photo (b&w)
Silvia Fre

2020. The main focus of our research is understanding how adult stem cells are maintained throughout life, how they generate and regenerate tissues and how they relate to tumor development. We focus on studying how the Notch signalling pathway controls cell fate specification and lineage segregation, in coordination with tissue...

rlevayer
Romain Levayer

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Lesterlin carré
Christian Lesterlin

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Bardin
Allison Bardin

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Christian Braendle
Christian Braendle

Christian Braendle is interested in understanding how environmental variation and genotype-environment interactions contribute to phenotypic variation. He is using the C. elegans model as well as closely related species to study how environmental variation modulates developmental processes and their phenotypic outcomes, including fitness consequences. ...

manolis
Manolis Papamichos-Chronakis

The overall objective of Manolis Papamichos-Chronakis group is to decipher the interplay between the multiple machineries that keep our genome intact and the chromatin structure of DNA. Using a combination of genetics, cell imaging and high-throughput technologies in budding yeast and human cells they are exploring the role of chromatin...

Journot
Laurent Journot

We each have two versions or alleles of each gene, one from our father, one from our mother. Parental genomic imprinting is an epigenetic mechanism that restrains the expression of an allele depending on its origin, paternal or maternal. 

The alteration of this process at defined loci results in different...

Benjamin Prud'homme
Benjamin Prud’homme

Animal’s morphological and behavioral traits are specified by genes during embryological development. Those traits change through species evolution via genetic modifications which are affecting developmental processes. Benjamin Prud’homme’s aim is to identify those genetic changes and to understand how they translate into morphological of behavioral modifications....

heard
Edith Heard

X-inactivation is a process by which one of the two X chromosomes is transcriptionally silenced during early development in female mammals. It allows for dosage compensation between XX females and XY males. Edith Heard is studying this paradigm for developmental epigenetics to gain insights into the fundamental mechanisms that underlie...