2019. Francesca Giordano and her team work to figure out the role of membrane contact sites or nearby membrane attachment sites (at 10-30nm) in the transport of lipids between endoplasmic reticulum and other intracellular organelles. The exchange of non-vesicular lipids at membrane contact sites emerges as one of the key...
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Jérôme Déjardin's lab is focused on understanding the contributions of heterochromatin factors and DNA repeats to genome stability, gene expression and genome evolution....
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[vc_row row_type="row" type="full_width" text_align="left" background_image="24" background_image_as_pattern="without_pattern"][vc_column width="1/1"][vc_separator type="transparent" position="center" down="50"][vc_row_inner row_type="row" type="grid" text_align="left"][vc_column_inner width="1/3"][vc_single_image image="1513" border_color="grey" img_link_target="_self" img_size="full" qode_css_animation="element_from_fade"][/vc_column_inner][vc_column_inner width="2/3" el_class="desc-laureat"][vc_column_text] [acf field="fser_nom"] [/vc_column_text][vc_column_text el_class="subtitle"][acf field="fser_year"] [acf field="fser_genre"] [portfolio_tags] [/vc_column_text][vc_separator type="transparent" position="center" down="20"][vc_column_text]Current position [acf field="fser_current_position"][/vc_column_text][vc_separator type="transparent" position="center" down="10"][vc_column_text]Host Institution [acf field="fser_host_institution"][/vc_column_text][vc_separator type="transparent" position="center" down="20"][vc_column_text][icons size='' custom_size='' icon='fa-globe' type='normal' position='left' border='no' border_color='' icon_color='#ffffff' background_color='' margin='0px 5px...
Lionel Navarro’s current research interests are to understand the role and regulation of small RNAs in plant and human innate immunity and to unravel the mechanisms by which bacterial effectors interfere with RNA silencing. His research also aims at deciphering the role of RNA silencing in the evolution of the...
Vertebrate blood vessels form stereotyped, hierarchical branched networks. Specialized endothelial cells (EC) called tip cells located at the extremities of growing capillary sprouts mediate their directional outgrowth. Research in Anne Eichmann’s laboratory is aimed at understanding the function of tip cell-specific signaling molecules, with the goal to manipulate guided vascular...
X-inactivation is a process by which one of the two X chromosomes is transcriptionally silenced during early development in female mammals. It allows for dosage compensation between XX females and XY males. Edith Heard is studying this paradigm for developmental epigenetics to gain insights into the fundamental mechanisms that underlie...
Bernardo Reina San Martin is interested in the molecular mechanisms driving the diversification of the repertoire of B-cells, the cells of our immune system producing antibodies. He specifically investigates somatic hypermutation (SHM) and class switch recombination (CSR), two processes involved in the immune response to generate an antibody mediated answer,...
In adults, cell renewal is precisely controlled, notably by a mechanism involving Dependence Receptors in the control of cell death. In certain cancers, cells escape this process, which gives them a supplementary selective advantage to uncontrollably multiply and form tumors. Patrick Mehlen deciphers those mechanisms to offer novel ways to...