François Leulier's research goals are twofold : first, he aims at deciphering the molecular dialogue governing the mutualistic interaction between intestinal bacteria and their host, especially in the context of juvenile growth, and second, he aims at translating this knowledge to mammalian models in order to consider applied solution to...
Food intake may dictate metabolic adaptations as well as the control of cell growth and proliferation. Mario Pende's goal is to better understand the coordination of these responses. He and his team are stuyding the protein kinase Target Of Rapamycin (TOR) which has an evolutionary conserved role in the integration...
Patrick Collombat and his research group are studying type I diabetes, an auto-immune disease characterized by the loss of insulin producing cells in the pancreas (the beta cells). Using mice as a model system, they recently demonstrated that ectopic expression of a single gene (Pax4) in neighboring cells of the...
Nathalie Vergnolle identifies and characterizes mediators of inflammation and pain in intestinal pathologies (Irritable Bowel Syndrome (IBS), Infectious Colitis, Inflammatory Bowel Diseases (IBD), and Inflammation-Associated Colorectal Cancers)....