Understanding how germ cells develop is not only of paramount medical interest for reproductive medicine, but is also crucial to comprehend how animal shapes and forms evolve through generations. Jean-René Huynh and his team are focusing on how the genetic information (through meiosis) and epigenetic information (through small RNAs)...
Rafal Ciosk's research focuses on understanding the mechanisms involved in cell fate commitment and reprogramming, universal biological processes. He is using a combination of molecular, biochemical and genomic approaches in the experimental model C. elegans to decipher the molecular regulation of pluripotency in germ cells, which involves mechanisms of mRNA...
How differentiated cells can change their identity is a fascinating question in biology and has implications for the development of regenerative medicine strategies. Numerous examples of cellular plasticity in physiological, experimental and pathological settings exist, but precisely how a differentiated cell can change its identity remains unknown. Sophie Jarriault tackle this...