Alexandre Puissant

Current position

Research Scientist (CRCN), Team Leader.

Host Institution

Jean Bernard Center, INSERM U944, St Louis Hospital; Paris, France.


3D illustration of blood circulating leukemic blasts

Molecular Mechanisms of Acute Myeloid Leukemia Development


Alexandre Puissant and his research group are investigating the cellular mechanisms underlying acute myeloid leukemia (AML) development and chemoresistance using cutting-edge screening technologies intended to modulate gene function. These technologies are applied on several mouse models of AML which reproduces closely the human pathology.

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• 2011: Doctor of Science, Ph.D., University of Nice-Sophia Antipolis, Nice, France, Patrick Auberger’s laboratory.

• 2011-2016: Post-doctoral fellow, Dana-Farber Cancer Institute & Harvard Medical School, Boston, MA, USA, Kimberly Stegmaier’s lab.

• 2016: Research Scientist (INSERM CRCN, permanent position).

• 2017: Group leader at the INSERM Unit U944, St Louis Hospital, Paris, France.


• 2017: Starting Grant from the European Research Council (ERC).

• 2017: ATIP/AVENIR Research Grant, French Educational and Research Ministry. Principal Investigator.

• 2016: Laurette Fugain Award, Laurette Fugain Association.

• 2011: Award for young researcher, Bettencourt-Schueller Foundation.