Bernardo Reina San Martin

Current position

Group leader, Research Director (DR2)

Host institution

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France Inserm, France

Molecular Biology of B cells


Bernardo Reina San Martin is interested in the molecular mechanisms driving the diversification of the repertoire of B-cells, the cells of our immune system producing antibodies. He specifically investigates somatic hypermutation (SHM) and class switch recombination (CSR), two processes involved in the immune response to generate an antibody mediated answer, which is long lasting and highly specific.

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• 2000 Ph. D. in Immunology, Pasteur Institute, Paris, France, Paola Minoprio's Lab, Evolution of the B cell repertoire during an infectious challenge with Trypanosoma cruzi

• 2000-2006 Post-doctoral fellow, The Rockfeller University, HHMI, New York, USA, Michel Nussenzweig's lab, Function of activation induced cytidine deaminase (AID) in B cell receptor diversification

• 2006 Appoint Group leader at the IGBMC, Strasbourg, France

• 2007 Appointed Inserm Scientist (CR1), Inserm, France

• 2010 Appointed Research Director (DR2), Inserm, France


• 2015 Laureate Association Alsace Contre le Cancer

• Elected member at The Henry Kunkel Society, USA, 2010

• Scientific Prize, Comité Alsace de la Fondation pour la Recherche Médicale (FRM), 2009

• AVENIR starting grant, Inserm, 2007

• Mexican’s National AIDS Research Award, Fondation pour la Recherche Médicale (FRM), 1995