Group leader, Professor
Université Libre de Bruxelles, Belgique
Clonal analysis of a developing tumor
The physiological process that maintains a constant number of cells in renewing organs is called tissue homeostasis. Stem cells located in these organs are responsible for the maintenance of tissue homeostasis during physiological condition and tissue repair following injuries. A better understanding of the mechanisms regulating stem cell function will have an important impact into the understanding and treatment of many pathological conditions such as cancer, degenerative diseases or ageing.
• 1995 MD., Université Libre de Bruxelles, Belgique
• 2001 PhD., Université Libre de Bruxelles, Belgique, Marc Parmentier’s lab
• 2002 Intern Certification in Medicine, Université Libre de Bruxelles, Belgique
• 2002-2006 Postdoctoral fellow, Rockfeller University, New-York, USA, Elaine Fuchs’ lab
• 2006 Appointed Group Leader at the Université Libre de Bruxelles, Belgique
• Starting and Consolidator ERC (European Research Council) Grants, 2008, 2013
• Elected EMBO member in 2012
• Outstanding Young Investigator Award, International Society for Stem Cell Research (ISSCR), 2012
• member of the Young Investigator Program, EMBO, 2009
• Career Developpement Award, Human Science Frontier Program, 2006-2009
P53 : La Proteine Anti-Tumeurs
Defining stem cell dynamics and migration during wound healing in mouse skin epidermis.
Mar 2017, Nat Commun.
Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.
Jan 2016, Nat Cell Biol.