Christian Braendle

Christian Braendle

Current position

Group leader, Research Director

Host institution

Institute of Biology Valrose, Nice, France CNRS, France

Microscope picture of the Nematode Caenorhabditis elegans

Gene-environment interactions in development and evolution



We study the evolution of development within species and populations, with a focus on the question of how genotype-by-environment interactions generate heritable variation in developmental processes and corresponding phenotypic outcomes. Although genotype-by-environment interactions are common and important determinants of phenotypic variation, the mechanisms by which genetic and environmental variation interact to generate trait variation remain poorly understood. Our projects thus aim to characterize the molecular and developmental basis of genotype-by-environment interactions, how such interactions evolve and how they in turn may impact the evolutionary process itself. In our research, we use the nematode Caenorhabditis elegans and related species as model organisms, and we integrate quantitative experimental approaches from developmental and evolutionary genetics.


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• 2003 : Ph. D. in Ecology and Evolutionary Biology, Princeton University, USA, David Stern's lab

• 2004-2007 : Post-doctoral fellow, Jacques Monod Institute, Paris, France, Marie-Anne Felix' lab

• 2008 : Post-doctoral fellow, Centre d'Immunologie Marseille-Luminy, Marseille, France, Jonathan Ewbank's lab


• Fellow at the Institute for Advanced Study (Wissenschaftskolleg), Berlin, 2012

• ATIP CNRS, 2008