Déborah Bourc'his

2010 Laureate

Current position

Senior group leader, Research Director (DR2)

Host institution

Curie Institute, Paris, France Inserm, France

Mouse embryos at different developmental stages

Epigenetics decisions and reproduction in mammals


Déborah Bourc’his is focused on understanding the role of epigenetics in mammalian reproduction. Her efforts with her team are mostly centered on DNA methylation, and they are addressing the following questions: How are DNA methylation patterns shaped? How do they impact germ cell identity and integrity? How much gametic DNA methylation is transmitted to the progeny and how does it influence phenotypes across generations?

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• 2000, PhD in Natural Sciences, Necker Hospital, France. Evani Viegas-Péguignot's lab, Genetic and embryonic origins of the DNA methylation defect observed in ICF patients.

• 2001-2005 Postdoctoral fellow at Columbia University, USA. Timothy Bestor’s Lab, Dnmt3L roles in genomic imprinting establishment and transposon control during mammalian gametogenesis

• 2005-2008 Research scientist at Paris 7 University, France, Genomic and functional characterization of genomic imprinting

• 2009 Appointed Team Leader, Institut Curie, Paris, France


• Liliane Bettencourt Prize for Life Sciences, Fondation Bettencourt Schueller, 2017

• Suffrage Award-Women in Science, MRC London, 2016

• Elected EMBO member, 2014

• Consolidator ERC (European Research Council) Grant 2013

• Jayle Prize, French Academy of Science, 2013

• European Young Investigator Award, European Science Foundation, 2006