2015 Laureate
Host Institution
Group leader, CR1 Inserm
Current position
CNRS UMR5535, IGMM - Institute of Molecular Genetics, Montpellier, France
eric.soler@igmm.cnrs.fr
Eric Soler and his research group are investigating mechanisms regulating spatio-temporal control of gene expression. They investigate the relationships existing between chromosome folding, genome architecture and gene expression during cellular differentiation and development. They use red blood cell differentiation as a model to conduct epigenomic studies of normal differentiation processes. They also investigate the genetic mechanisms of both frequent and rare red blood cells disorders such as beta-thalassemia and erythroid leukemias.
• 2016 : Habilitation à diriger des recherches (HDR), Université de Montpellier
• 2016 : Appointed Team Leader at the IGMM (Molecular Genetics Institute of Montpellier), France
• 2014 : Appointed Atip-Avenir Group leader at Inserm UMR967, CEA iRCM institute, Fontenay-aux-Roses, France
• 2013 : Appointed Research associate (Inserm CR1, permanent position), Inserm UMR967, Fontenay-aux-Roses, France
•2010-2012 : Appointed Group Leader at the Erasmus Medical Center, Rotterdam, The Netherlands
• 2006-2010 : Postdoctoral fellow, Erasmus Medical Center, Rotterdam, the Netherlands, Frank Grosveld's lab
• 2005 PhD, Université Paris 7, France, Louis-Marie Houdebine's lab
• Member of the Laboratory of Excellence (LabEx) EpiGenMed, Montpellier, 2016
• Member of the LabEx on Red Blood Cells GR-Ex, 2015
• Atip-Avenir Grant, (Inserm), 2013
Control of developmentally primed erythroid genes by combinatorial co-repressor actions
Nov 2015, Nat Commun.
Long-range gene regulation and novel therapeutic applications
March 2015, Blood
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers
April 2014, J Clin Invest