Franck Oury

Current position

Group leader, CR1-INSERM

Host institution

Institut Necker Enfants-Malades (INEM) – INSERM U1151 – Université Paris V


Hormonal regulation of brain development and cognitive functions


Franck Oury and his research group are investigating how hormonal systems influence brain development and cognitive functions. Hormones are crucial for the maintenance of whole-body homeostasis by mediating crosstalk between organs. However, many of them can also reach the central nervous system where they help shape the developing brain, affect cognition, and contribute to brain aging and neurodegenerative diseases.


The major axes of his current research are: i) To study whether additional hormonal signaling pathway(s) are involved in the regulation of brain development and cognitive functions ; ii) To determine the cellular and molecular mechanisms elicited by hormones in neuronal cells; iii) To characterize the deleterious effect of hormonal imbalances during aging on the cognitive decline and development of neurodegenerative diseases.Indeed, the work proposed here may open a new area of investigation in endocrinology and neurobiology, and lead to novel therapeutic avenues for metabolic and cognitive disorders.

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• 2014: Group leader position, Institut Necker Enfants-Malades (INEM), Université Paris V, Paris, France

• 2011-2013: Associate Research Scientists, Columbia University – Medical Center, New York, USA, Dept: Genetics and Development, Laboratory: Gérard KARSENTY

• 2007-2010: Postdoc, Columbia University – Medical Center, New York, USA, Dept: Genetics and Development, Laboratory: Gérard KARSENTY

• 2002-2006: PhD, Institut de Génétique et Biologie Cellulaire et Moléculaire (IGBMC) - Université Louis Pasteur, Strasbourg, France, Dept: Development, Laboratory : Prof. Filippo RIJLI


• Human frontiers Science Program - Career Developmental Award (CDA), 2015

• Fondation pour la Recherche Medicale - Amorcage Jeunes équipes Program, 2013

• Rupert Timpl Award - International Society for Matrix Biology, 2014

• Blavatnik Young Investigator Award (The New York Academy of Sciences), 2011

• ASBMR Young Investigator award, 2011

• EMBO long-term fellowship awards, 2008

• Bettencourt-Schueller Fondation Young investigator award, 2007

• Philippe Fondation Young investigator award (prize September, 2007