Frederic Landmann

F. Landmann - Photo

Frederic Landmann

Current position

Group Leader CNRS, CR

Host institution

CRBM, Montpellier

 The female germline of Brugia malayi, a filarial nematode causing human filariasis, is aberrant upon Wolbachia endosymbionts depletion.

A wild-type filarial germline with Wolbachia (-in pink, top image) and aberrant after Wolbachia depletion (bottom). DNA is in blue and actin in yellow.

Mechanisms of symbiosis with Wolbachia in filarial nematodes

Frederic Landmann and his team are exploring the symbiotic relationship between Wolbachia bacteria and their parasitic hosts, the filarial nematodes.  These worms cause debilitating diseases, the filariasis, and infect 100 million people. They rely on intracellular Wolbachia endosymbionts to produce a progeny and to survive. We are investigating the intracellular lifestyle of Wolbachia, and why these endosymbionts are vital for the worms, since they offer a way to cure the disease being therapeutical targets.

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PhD : 2005 Université Louis Pasteur, Strasbourg, IGBMC, with Dr Michel Labouesse.

Postdoc: 2005-2013 , UCSC, Santa Cruz, CA, USA, with Prof. William Sullivan

1st group leader position:
2013, CNRS, CRBM, Montpellier