Jean-Laurent Casanova

2001 Laureate

Current position

Professor at the Rockfeller University, HHMI Investigator, Senior attending physician at the Rockfeller Hospital, Head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, Visiting Professor, Hôpital Necker

Host institution

The Rockfeller University, New York, The Howard Hughes Medical Institute USA, Necker Hospital for Sick Children, Paris, France

Genetics of human predisposition to pediatric infectious diseases


In paradigm‐ shifting discoveries reported over two decades, Jean‐ Laurent Casanova has uncovered that life-threatening infectious diseases striking otherwise healthy children may be caused by single‐ gene inborn errors of immunity. Pursuing both biological and medical goals, he attempts to establish a genetic theory of childhood infectious diseases.

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•1987 : M.D. , University Paris 5 Descartes, France

•1992 : Ph. D. in Biology, University Paris 6 UPMC, Pasteur Institute and Ludwig Institute for Cancer Research, France & Switzerland, Janet Maryanski's lab

•1999 : Appointed Professor of Pediatrics, Necker Hospital, Paris, France

•1999 : Appointed Head of laboratory (with Laurent Abel), Necker Hospital, Paris, France



•AAI-Steinman Award for Human Immunology Research, American Association of Immunologists (AAI), 2017

•"Grand prix" Inserm, 2016

•Robert Koch Prize, Germany, 2014

•HHMI Investigator Appointment, USA, 2013

•Ilse and Helmut Wachter Foundation Award, Innsbruck Medical University, Austria, 2012

•Seymour and Vivian Milstein Award, USA, 2012

•InBev-Baillet Latour Health Prize, Immunology and Infectious Diseases, Belgium, 2011