Leïla Perié

Our research focuses on understanding hematopoiesis, the fascinating process through which stem cells in our bone marrow give rise to all the different types of blood and immune cells in our bodies. These cells are constantly being replenished because most of them have short lifespans.
We’re particularly interested in how this process works at the level of individual cells. Imagine each blood cell as a member of a big family tree, with stem cells at the top giving rise to various “descendants.” We use advanced techniques, including Genealomics, which involves high-tech sequencing methods, to track the family tree of these cells. This allows us to see how individual cells develop and relate to each other over time.
By combining experimental and computational approaches, we aim to unravel the complexities of hematopoiesis and how it responds to different situations, like infections or bleeding. Understanding this process could lead to insights into various diseases and help develop better treatments in the future.